Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421974 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10490953 | 0.80 | KDM1A (0.41) | MAPT | |
| SCHEMBL10490943 | 0.80 | HDAC4 (0.47) | ALDH1A1TSHRHSD17B10HPGDMAPK1 | |
| SCHEMBL17401225 | 0.75 | HTR2A (0.41) | ALDH1A1MAPTHSD17B10HPGDLMNA | |
| SCHEMBL12251168 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTHSD17B10TDP1HPGD | |
| SCHEMBL14113261 | 0.74 | MAOA (0.56) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10490941 | 0.73 | NPC1 (0.47) | MAPTMAOAHPGDSMN1; SMN2 | |
| SCHEMBL10490934 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL14008637 | 0.72 | MAOA (0.39) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL8559808 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPTALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843097-A | ANTITUMOR AGENTS, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-06-27 | — | — | US | claimed |
| US-4889865-A | COSMETICS, SKIN DISORDERS, ANTICARCINOGENIC AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-12-26 | — | — | US | disclosed |
| US-4843097-A | ANTITUMOR AGENTS, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-06-27 | — | — | US | disclosed |