Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492071 | 0.86 | CA12 (0.48) | FAAHLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14800515 | 0.74 | MAPT (0.50) | FAAHLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20269905 | 0.74 | LMNA (0.50) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL26659222 | 0.74 | ALDH1A1 (0.51) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3664984 | 0.74 | SMN1; SMN2 (0.68) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1894879 | 0.74 | LMNA (0.52) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL4692437 | 0.73 | FAAH (0.58) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL26638897 | 0.73 | LMNA (0.45) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1850876 | 0.72 | LMNA (0.51) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7698241 | 0.72 | LMNA (0.61) | FAAHLMNAALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4795817-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| WO-1985001732-A1 | 8-SUBSTITUTED PYRAZOLOPENTATHIEPINS AND RELATED COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-25 | — | — | WO | disclosed |
| EP-0138622-A2 | 8-substituted pyrazolopentathiepins and related compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |