SCHEMBL1894879

SCHEMBL1894879

CCOC(=O)c1cc(C)nn1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
SMN1; SMN2 Q16637 5/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
MAPT P10636 1/20 0.51
KDM4E B2RXH2 2/20 0.49
KMT2A Q03164 3/20 0.44
FAAH O00519 2/20 0.44
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
TSHR P16473 1/20 0.42
JMJD6 Q6NYC1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28174776 0.88 LMNA (0.44) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL15233727 0.85 ESR1 (0.48) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL7698241 0.84 LMNA (0.61) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL1850876 0.84 LMNA (0.51) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL20177039 0.83 LMNA (0.53) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL26104183 0.83 RAB9A (0.54) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL286585 0.83 LMNA (0.50) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL973113 0.83 LMNA (0.50) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL8072052 0.83 LMNA (0.56) LMNASMN1; SMN2NPC1RAB9AMAPT
SCHEMBL20269905 0.83 LMNA (0.50) LMNASMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049827-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING PYRAZOLE DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO claimed
CN-111825617-B Method for preparing 1, 3-dimethyl-4-chloromethylpyrazole-5-formate intermediate 南通江山农药化工股份有限公司 2023-08-29 CN claimed
CN-113292496-B Synthetic method of Laratinib intermediate 安徽联创生物医药股份有限公司 2023-03-10 CN claimed
CN-112279812-A Synthetic method of 1, 3-dimethyl-1H-pyrazole-5-ethyl formate 南京哈柏医药科技有限公司 2021-01-29 CN claimed
CN-107216288-A A kind of preparation method of Tolfenpyrad impurity 湖南大学 2017-09-29 CN claimed
EP-1248781-A1 PYRAZOLE CYCLIC AMP-SPECIFIC PDE INHIBITORS ICOS CORPORATION (US) 2002-10-16 EP claimed
WO-2001046172-A1 PYRAZOLE CYCLIC AMP-SPECIFIC PDE INHIBITORS ICOS CORPORATION (US) 2001-06-28 WO claimed
JP-10053582-A None JP disclosed
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
WO-2026101971-A2 EGFR INHIBITORS FOR TREATING DISEASE BLOSSOMHILL THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
EP-3365339-B1 NOVEL FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-07-16 EP disclosed
WO-2025049827-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING PYRAZOLE DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
US-4792565-A Pyrazolecarbonylamine derivatives and agricultural and horticultural fungicides containing said compounds MITSUI TOATSU CHEMICALS, INC. (JP) 1988-12-20 US disclosed
EP-0087780-A2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1983-09-07 EP disclosed
US-4389406-A ANTHELMINTICS BEECHAM GROUP LIMITED (GB) 1983-06-21 US disclosed
EP-0041322-A1 m-Pyrazolylamido tetramisole derivatives, compositions thereof, processes for production of such compounds and compositions and their use in treating helminthiasis BEECHAM GROUP PLC (GB) 1981-12-09 EP disclosed
US-4214090-A Fungicidal carboxamidopyrazoles COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AT) 1980-07-22 US disclosed
US-4134987-A PYRAZOLE DERIVATIVES, FUNGICIDES HUPPATZ JOHN L 1979-01-16 US disclosed