Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.39 |
| ▸ | HTR1B | P28222 | 6/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1049681 | 0.99 | HTR1D (0.39) | HTR1DHTR1BPTGS2TRPV1HTR1A | |
| Hydrochloric Acid SCHEMBL1048916 | 0.87 | HTR1D (0.36) | HTR1DHTR1BPTGS2TRPV1HTR1A | |
| Hydrochloric Acid SCHEMBL1050543 | 0.86 | TRPV1 (0.36) | HTR1DPTGS2TRPV1HTR1AHTR2B | |
| SCHEMBL5050472 | 0.86 | HTR1D (0.35) | HTR1DHTR1BPTGS2TRPV1SPR | |
| Hydrochloric Acid SCHEMBL5164080 | 0.85 | HTR1D (0.40) | HTR1DHTR1BPTGS2TRPV1HTR1A | |
| SCHEMBL3769416 | 0.84 | HTR1D (0.38) | HTR1DHTR1BPTGS2TRPV1SPR | |
| SCHEMBL4539260 | 0.84 | HTR1D (0.38) | HTR1DHTR1BPTGS2TRPV1SPR | |
| SCHEMBL1051771 | 0.82 | ACHE (0.33) | HTR1DHTR1BPTGS2TRPV1SPR | |
| Hydrochloric Acid SCHEMBL1051875 | 0.80 | HTR1D (0.38) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL1047567 | 0.79 | HTR1D (0.39) | HTR1DHTR1BPTGS2TRPV1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868036-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-01-11 | — | — | US | disclosed |
| US-20080058320-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058320-A1 | Organic Compounds | REN, AGTR1, ADH1C | HTR1D 698/4885HTR1B 517/4885PTGS2 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.