Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563148 | 0.74 | KDM4E (0.41) | ALDH1A1KDM4EGAAGLAHSD17B10 | |
| SCHEMBL7817859 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL5815734 | 0.70 | KDM4E (0.53) | ALDH1A1KDM4EGAAGLAHSD17B10 | |
| SCHEMBL7817258 | 0.70 | GPR174 (0.72) | ALDH1A1GAAKMT2AMEN1ABCC9 | |
| SCHEMBL29538575 | 0.69 | GAA (0.61) | ALDH1A1KDM4EGAAGLAHSD17B10 | |
| SCHEMBL7817092 | 0.67 | GPR174 (0.70) | KDM4EKMT2AMEN1ABCC9ABCC8 | |
| SCHEMBL7820326 | 0.67 | ALDH1A1 (0.67) | ALDH1A1KDM4EGAAGLAHSD17B10 | |
| SCHEMBL8085348 | 0.65 | CRBN (0.38) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL9803041 | 0.64 | KDM4E (0.35) | ALDH1A1KDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL22269163 | 0.63 | ALDH1A1 (0.33) | ALDH1A1KDM4EGAAHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814280-A | FLUORIGENIC ASSAY | PETERSON CHARLES M (US) | 1989-03-21 | — | — | US | claimed |
| US-4814280-A | FLUORIGENIC ASSAY | PETERSON CHARLES M (US) | 1989-03-21 | — | — | US | disclosed |