Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807801 | 0.86 | CRBN (0.40) | CRBNMAPTMEN1KMT2AGAA | |
| SCHEMBL17582652 | 0.79 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9802754 | 0.76 | CRBN (0.46) | CRBNMAPTMEN1KMT2AGAA | |
| SCHEMBL5696232 | 0.73 | CRBN (0.32) | CRBNMAPTMEN1KMT2AGAA | |
| SCHEMBL30938423 | 0.72 | PTK2 (0.36) | GAAALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5177304 | 0.70 | ALDH1A1 (0.40) | CRBNMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL31358559 | 0.69 | IDH1 (0.34) | CRBNMAPTMEN1KMT2AGAA | |
| SCHEMBL11765567 | 0.69 | MEN1 (0.32) | MAPTMEN1KMT2AGAAPABPC1 | |
| SCHEMBL9803041 | 0.69 | KDM4E (0.35) | CRBNGAAALDH1A1KDM4ELMNA | |
| SCHEMBL10668871 | 0.67 | OR51E2 (0.42) | CRBNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976042-B1 | 9-(5-bromo-2-hydroxyphenyl)-10-[3-(dimethylamino)propyl]-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11939316-B1 | 9-(6-flouro-2-hydroxyouinolin-3-yl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexhydroacridine-1,8(2h,5h)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-03-26 | — | — | US | disclosed |
| US-11926610-B1 | 9-(2-hydroxypyridin-3-yl)10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-03-12 | — | — | US | disclosed |
| US-11919878-B1 | 9-(2-hydroxypyridin-3-yl)-10-(2-phenylethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound | King Faisal University (SA) | 2024-03-05 | — | — | US | disclosed |
| US-6121284-A | SPECIFIED 1-(ALKYL OR CYCLOALKYL)-2-METHYL-3-(ALKOXYCARBONYL)-4-(SUBSTITUTED PYRIDYL OR ARYL)-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE COMPOUNDS; TREATING SICKLE CELL ANEMIA, PSYCHOSES, DEPRESSION | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| EP-0705830-A1 | 2,3-Cyclic condensed 1,4-dihydropyridines, process for their preparation and their use as K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939316-B1 | 9-(6-flouro-2-hydroxyouinolin-3-yl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexhydroacridine-1,8(2h,5h)-dione as an antimicrobial compound | Q6ZSR9, FPR2, HSPH1 | CRBN 3547/4885MAPT 4005/4885MEN1 3432/4885 |
| US-11926610-B1 | 9-(2-hydroxypyridin-3-yl)10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound | DNASE1, TLR1, MPO | CRBN 4040/4885MAPT 4224/4885MEN1 3820/4885 |
| US-11976042-B1 | 9-(5-bromo-2-hydroxyphenyl)-10-[3-(dimethylamino)propyl]-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione as an antimicrobial compound | MPO, AMPD1, MRPL21 | CRBN 3609/4885MAPT 4227/4885MEN1 3544/4885 |
| US-11919878-B1 | 9-(2-hydroxypyridin-3-yl)-10-(2-phenylethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound | MPO, TLR1, TLR5 | CRBN 3441/4885MAPT 3458/4885MEN1 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.