Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.32 |
| ▸ | MAOB | P27338 | 7/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 3/20 | 0.31 |
| ▸ | CTSB | P07858 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051706 | 0.75 | ALDH1A1 (0.39) | MAOAMAOBCTSLCTSBCTSK | |
| SCHEMBL1051705 | 0.75 | ALDH1A1 (0.39) | MAOAMAOBCTSLCTSBCTSK | |
| SCHEMBL11823681 | 0.71 | MAOA (0.48) | MAOAMAOBDPP4OPRM1OPRL1 | |
| SCHEMBL4014136 | 0.71 | CTSL (0.41) | DPP4OPRM1OPRL1ALOX15CTSL | |
| SCHEMBL8767085 | 0.69 | MAOA (0.47) | MAOAMAOBCTSLCTSBCTSK | |
| SCHEMBL20121045 | 0.66 | CTSL (0.45) | DPP4OPRM1OPRL1ALOX15CTSL | |
| SCHEMBL20121044 | 0.66 | CTSL (0.45) | DPP4OPRM1OPRL1ALOX15CTSL | |
| SCHEMBL22111662 | 0.66 | OPRM1 (0.48) | DPP4OPRM1OPRL1CTSLCTSB | |
| SCHEMBL11171764 | 0.65 | ALOX15 (0.35) | ALOX15 | |
| SCHEMBL31570432 | 0.65 | CTSL (0.38) | DPP4OPRM1OPRL1ALOX15CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872034-B2 | Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-01-18 | — | — | US | disclosed |