Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269441 | 0.86 | ALDH1A1 (0.65) | MAPTKMT2AALDH1A1RAB9ACES2 | |
| SCHEMBL1603880 | 0.85 | MAPT (0.50) | MAPTKMT2AALDH1A1ESR2RAB9A | |
| SCHEMBL24654488 | 0.84 | CES2 (0.59) | MAPTKMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL29763732 | 0.84 | CES2 (0.59) | MAPTKMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL10499520 | 0.83 | ELANE (0.49) | MAPTKMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL10500154 | 0.80 | LMNA (0.46) | MAPTKMT2AALDH1A1CES2CES1 | |
| SCHEMBL12700321 | 0.77 | CES2 (0.83) | MAPTKMT2AALDH1A1ESR2RAB9A | |
| SCHEMBL1817437 | 0.77 | MAPT (0.68) | MAPTKMT2AALDH1A1ESR2RAB9A | |
| SCHEMBL19018122 | 0.77 | MAPT (0.68) | MAPTKMT2AALDH1A1ESR2RAB9A | |
| Mequinol SCHEMBL28560858 | 0.77 | ESR2 (0.80) | KMT2AESR2RAB9ACALM1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849419-A | 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-07-18 | — | — | US | disclosed |
| EP-0174561-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |
| US-4131470-A | THIOCARBOXYLATES | VEB FILMFABRIK WOLFEN (DE) | 1978-12-26 | — | — | US | disclosed |