SCHEMBL269441

SCHEMBL269441

COc1ccc(C(=O)Sc2ccc(C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
MAPT P10636 4/20 0.65
KMT2A Q03164 2/20 0.62
LMNA P02545 2/20 0.62
HTT P42858 1/20 0.62
HPGD P15428 2/20 0.60
NPC1 O15118 3/20 0.53
RAB9A P51151 1/20 0.53
ACHE P22303 1/20 0.52
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
TP53 P04637 1/20 0.49
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
PARP1 P09874 1/20 0.47
PARP10 Q53GL7 1/20 0.47
PARP2 Q9UGN5 1/20 0.47
PARP4 Q9UKK3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21186186 0.87 ALDH1A1 (0.64) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL13415409 0.87 ALDH1A1 (0.64) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL25491800 0.87 ALDH1A1 (0.64) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL10499758 0.86 MAPT (0.50) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL24654488 0.84 CES2 (0.59) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL29763732 0.84 CES2 (0.59) ALDH1A1MAPTKMT2AHPGDNPC1
SCHEMBL10499520 0.83 ELANE (0.49) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL21185915 0.83 ALDH1A1 (0.54) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL31054336 0.80 MAPT (0.57) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL10500154 0.80 LMNA (0.46) ALDH1A1MAPTKMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724773-A Novel method for preparing thioester by using visible light catalytic sulfonium salt without participation of transition metal 郑州大学 2024-10-01 CN disclosed
US-20180052111-A1 SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS PLATYPUS TECHNOLOGIES, LLC 2018-02-22 US disclosed
US-9816147-B2 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2017-11-14 US disclosed
US-9816147-B2 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2017-11-14 US disclosed
US-9797843-B2 Substrates, devices, and methods for quantitative liquid crystal assays PLATYPUS TECHNOLOGIES, LLC (US) 2017-10-24 US disclosed
US-9797843-B2 Substrates, devices, and methods for quantitative liquid crystal assays PLATYPUS TECHNOLOGIES, LLC (US) 2017-10-24 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-7662572-B2 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC. (US) 2010-02-16 US disclosed
US-7651662-B2 Rubbed substrate surfaces; activation; uniform anchoring of liquid crystals WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-01-26 US disclosed
US-20100009344-A1 LIQUID CRYSTAL BASED ANALYTE DETECTION PLATYPUS TECHNOLOGIES, LLC (US) 2010-01-14 US disclosed
US-7531366-B2 Bead based assays using a liquid crystal reporter PLATYPUS TECHNOLOGIES, LLC (US) 2009-05-12 US disclosed
US-20080268546-A1 DETECTION OF DNA HYBRIDIZATION ON SURFACES WISCONSIN ALUMNI RESEARCH FOUNDATION 2008-10-30 US disclosed
US-20080160539-A1 Substrates, devices, and methods for cellular assays PLATYPUS TECHNOLOGIES, LLC (US) 2008-07-03 US disclosed
US-20070178534-A1 Using liquid crystal support comprising chemotactic and chemokinetic agents to monitor cell migration and invasion; diagnosing cancer NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-08-02 US disclosed
US-20070099249-A1 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2007-05-03 US disclosed
US-20070042505-A1 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2007-02-22 US disclosed
US-20070004046-A1 Detection of analytes PLATYPUS TECHNOLOGIES, LLC (US) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099249-A1 Compositions and liquid crystals FABP5, FABP1, SSB ALDH1A1 4540/4885MAPT 779/4885KMT2A 4615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.