Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501845 | 0.84 | KDM4E (0.31) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL5916810 | 0.83 | METAP2 (0.40) | ALDH1A1TDP1KDM4EKAT2BGAA | |
| SCHEMBL5916770 | 0.83 | METAP2 (0.40) | ALDH1A1TDP1KDM4EKAT2BGAA | |
| SCHEMBL5916643 | 0.77 | MPI (0.44) | ALDH1A1TDP1KDM4EKAT2BGAA | |
| SCHEMBL10501508 | 0.77 | METAP2 (0.42) | ALDH1A1TDP1KDM4EKAT2BGAA | |
| SCHEMBL10748041 | 0.77 | METAP2 (0.38) | ALDH1A1TDP1KDM4EKAT2BMAPT | |
| SCHEMBL5916638 | 0.76 | METAP2 (0.54) | ALDH1A1TDP1KDM4EKAT2BGAA | |
| SCHEMBL10502166 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TDP1KDM4EKAT2BGAA | |
| SCHEMBL10502494 | 0.74 | TXNRD1 (0.52) | ALDH1A1KDM4EKAT2BKMT2ARXFP1 | |
| SCHEMBL5916699 | 0.74 | METAP2 (0.46) | ALDH1A1KDM4EKAT2BKMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |