Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503662 | 0.86 | EP300 (0.36) | FBP1CYP3A4SCDSCN9AKIF11 | |
| SCHEMBL10501085 | 0.83 | MAPT (0.33) | FBP1CYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL10501096 | 0.81 | KDM4E (0.34) | FBP1KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL10502269 | 0.81 | MAPT (0.33) | FBP1CYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL10746681 | 0.79 | MAT2A (0.41) | KIF11ADRB2NCF1 | |
| SCHEMBL10501622 | 0.78 | RAB9A (0.43) | FBP1HDAC8KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL10501841 | 0.77 | KDM4E (0.41) | CYP3A4SCDNCF1KDM4EALDH1A1 | |
| SCHEMBL10502254 | 0.76 | SLC11A2 (0.39) | KIF11KDM4EALDH1A1GAA | |
| SCHEMBL10501845 | 0.75 | KDM4E (0.31) | FBP1KDM4EALDH1A1 | |
| SCHEMBL10501664 | 0.74 | G6PD (0.40) | CYP3A4KIF11NCF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |