Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | G6PD | P11413 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916638 | 0.83 | METAP2 (0.54) | KDM4EALDH1A1MAPTG6PDPKM | |
| SCHEMBL10501573 | 0.80 | MAPT (0.33) | KDM4EALDH1A1MAPTG6PDPKM | |
| SCHEMBL10501096 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1MAPTG6PDPKM | |
| SCHEMBL10502269 | 0.80 | MAPT (0.33) | KDM4EALDH1A1MAPTG6PDPKM | |
| SCHEMBL10501085 | 0.80 | MAPT (0.33) | KDM4EALDH1A1MAPTG6PDPKM | |
| SCHEMBL10501833 | 0.77 | NPC1 (0.43) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10501622 | 0.77 | RAB9A (0.43) | KDM4EALDH1A1MAPTKAT2BKMT2A | |
| SCHEMBL10501689 | 0.77 | FBP1 (0.35) | KDM4EALDH1A1GAACYP3A4NCF1 | |
| SCHEMBL10501845 | 0.77 | KDM4E (0.31) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10749736 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1MAPTG6PDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |