Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | MPI | P34949 | 2/20 | 0.37 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022181 | 0.84 | METAP2 (0.36) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL5916901 | 0.82 | METAP2 (0.54) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10502218 | 0.80 | CYP1A2 (0.47) | ALDH1A1CYP2C9CYP2C19METAP2POLB | |
| SCHEMBL10744532 | 0.79 | HRH4 (0.44) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10747582 | 0.78 | METAP2 (0.40) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10501811 | 0.76 | MPI (0.48) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10501737 | 0.76 | METAP2 (0.41) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10502474 | 0.75 | ALDH1A1 (0.38) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10501640 | 0.73 | METAP2 (0.37) | NPSR1MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10744770 | 0.73 | KDM4E (0.44) | NPSR1MEN1KMT2AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |