Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | PMM2 | O15305 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502118 | 0.84 | NPSR1 (0.44) | METAP2MPIPHOSPHO1NPSR1KDM4E | |
| SCHEMBL10744532 | 0.81 | HRH4 (0.44) | METAP2MPIPHOSPHO1NPSR1CYP2A6 | |
| SCHEMBL10744770 | 0.75 | KDM4E (0.44) | METAP2MPIPHOSPHO1NPSR1CYP2A6 | |
| SCHEMBL10502530 | 0.75 | MPI (0.41) | METAP2MPIPHOSPHO1CYP2A6ALDH1A1 | |
| SCHEMBL10501684 | 0.74 | SMN1; SMN2 (0.45) | METAP2MPIPHOSPHO1KDM4EALDH1A1 | |
| SCHEMBL10747582 | 0.73 | METAP2 (0.40) | METAP2MPIPHOSPHO1NPSR1KDM4E | |
| SCHEMBL10501737 | 0.72 | METAP2 (0.41) | METAP2MPIPHOSPHO1NPSR1CYP2A6 | |
| SCHEMBL10501811 | 0.72 | MPI (0.48) | METAP2MPIPHOSPHO1NPSR1KDM4E | |
| SCHEMBL10502474 | 0.71 | ALDH1A1 (0.38) | METAP2MPIPHOSPHO1NPSR1KDM4E | |
| SCHEMBL10502218 | 0.70 | CYP1A2 (0.47) | METAP2KDM4EALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |