Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916849 | 0.86 | LMNA (0.48) | CYP1A2CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL10749232 | 0.81 | CYP1A2 (0.48) | CYP1A2ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL10501763 | 0.80 | ALDH1A1 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL10502118 | 0.80 | NPSR1 (0.44) | CYP2C9CYP2C19ALDH1A1LMNAPOLB | |
| SCHEMBL10748117 | 0.79 | PIN1 (0.45) | — | |
| SCHEMBL10502534 | 0.74 | MPI (0.51) | CYP1A2ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL10501435 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1LMNAMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10747422 | 0.74 | MEN1 (0.41) | CYP2C9CYP2C19ALDH1A1LMNAPOLB | |
| SCHEMBL10744532 | 0.74 | HRH4 (0.44) | CYP2C9CYP2C19ALDH1A1LMNAPOLB | |
| SCHEMBL10747582 | 0.73 | METAP2 (0.40) | CYP2C9CYP2C19ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |