Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 2/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501265 | 0.90 | MPI (0.49) | METAP2ALDH1A1TDP1TSHRMPI | |
| SCHEMBL10502027 | 0.86 | METAP2 (0.62) | METAP2MPIPHOSPHO1 | |
| SCHEMBL10501110 | 0.80 | METAP2 (0.47) | METAP2ALDH1A1TSHRMPIPHOSPHO1 | |
| SCHEMBL10501645 | 0.80 | MPI (0.54) | METAP2ALDH1A1MPIPHOSPHO1MAPT | |
| SCHEMBL10503512 | 0.79 | ALDH1A1 (0.44) | METAP2ALDH1A1TDP1MPIPHOSPHO1 | |
| SCHEMBL10501312 | 0.78 | MEN1 (0.46) | METAP2ALDH1A1TSHRMPIMAPT | |
| SCHEMBL10501742 | 0.78 | METAP2 (0.47) | METAP2MPIPHOSPHO1 | |
| SCHEMBL10502541 | 0.78 | METAP2 (0.47) | METAP2ALDH1A1MPIPHOSPHO1 | |
| SCHEMBL10501811 | 0.76 | MPI (0.48) | METAP2ALDH1A1TDP1MPIPHOSPHO1 | |
| SCHEMBL10501435 | 0.76 | SMN1; SMN2 (0.45) | METAP2ALDH1A1TDP1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |