Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | ESRRG | P62508 | 2/20 | 0.51 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428090 | 0.89 | DRD4 (0.63) | ALDH1A1GAADRD4HRH3ACHE | |
| SCHEMBL23775627 | 0.85 | DRD4 (0.51) | ALDH1A1GAAMAPTDRD4MBTD1 | |
| SCHEMBL2477654 | 0.84 | LMNA (0.67) | ALDH1A1MAPTDRD4ESRRGHRH3 | |
| SCHEMBL10502663 | 0.82 | SIGMAR1 (0.68) | ALDH1A1MAPTDRD4CCR3SIGMAR1 | |
| SCHEMBL9720752 | 0.82 | DRD4 (0.77) | GAADRD4ACHESIGMAR1 | |
| SCHEMBL9720795 | 0.81 | CCR2 (0.54) | DRD4CCR3L3MBTL1SIGMAR1 | |
| SCHEMBL322305 | 0.81 | HRH3 (0.74) | ALDH1A1DRD4MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL10502907 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CCR3MBTD1L3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10503565 | 0.80 | SIGMAR1 (0.66) | ALDH1A1MAPTDRD4CCR3SIGMAR1 | |
| SCHEMBL10686392 | 0.80 | SIGMAR1 (0.60) | MAPTCCR3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122488-B1 | BIS-(PIPERAZINYL- OR HOMOPIPERAZINYL)-ALKANES | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1989-06-07 | — | — | EP | disclosed |
| US-4725597-A | ANTIALLERGEN, ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM LTD. (US) | 1988-02-16 | — | — | US | disclosed |
| EP-0122488-A1 | Bis-(piperazinyl- or homopiperazinyl)-alkanes | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1984-10-24 | — | — | EP | disclosed |