Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7581612 | 0.94 | ALPL (0.53) | ALPLPOLBALPGNPC1RAB9A | |
| Bicarbonate SCHEMBL7573060 | 0.94 | ALPL (0.53) | ALPLPOLBALPGNPC1RAB9A | |
| Acetic Acid SCHEMBL8664510 | 0.92 | ALPL (0.52) | ALPLPOLBALPGNPC1RAB9A | |
| Benzoic Acid SCHEMBL11538206 | 0.86 | CA2 (0.57) | ALPLPOLBALPGNPC1RAB9A | |
| SCHEMBL17438433 | 0.86 | NPC1 (0.49) | ALPLPOLBALPGNPC1RAB9A | |
| SCHEMBL486540 | 0.86 | NPC1 (0.45) | ALPLPOLBALPGNPC1RAB9A | |
| SCHEMBL239595 | 0.82 | ALPL (0.44) | ALPLPOLBALPGNPC1RAB9A | |
| SCHEMBL17438432 | 0.82 | MMP8 (0.48) | ALPLPOLBALPGNPC1RAB9A | |
| Bromide SCHEMBL515994 | 0.82 | SIGMAR1 (0.54) | TAAR1MEN1KMT2ATRPA1SLC6A2 | |
| SCHEMBL9752209 | 0.82 | SIGMAR1 (0.54) | TAAR1MEN1KMT2ATRPA1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274255-A2 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDER USING ONIUM DICARBOXYLATES | Sachem, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7867471-B2 | Process for preparing advanced ceramic powders using onium dicarboxylates | SACHEM, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| WO-2010011373-A2 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDER USING ONIUM DICARBOXYLATES | SACHEM, INC. (US) | 2010-01-28 | — | — | WO | disclosed |
| US-20090250850-A1 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDERS USING ONIUM DICARBOXYLATES | SACHEM, INC. | 2009-10-08 | — | — | US | disclosed |