Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508097 | 1.00 | PRMT5 (0.53) | PRMT5WDR77CYP2D6CYP2C9HIF1A | |
| SCHEMBL10504734 | 0.82 | PRMT5 (0.55) | PRMT5WDR77FAAH | |
| SCHEMBL13293358 | 0.81 | ITGB3 (0.61) | CYP2D6CYP2C9HIF1AFAAHHRH3 | |
| SCHEMBL9866734 | 0.80 | PRMT5 (0.64) | PRMT5WDR77CYP2D6HIF1A | |
| SCHEMBL6140348 | 0.80 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL13574528 | 0.80 | HRH2 (0.56) | CYP2D6CYP2C9HIF1AFAAHHRH3 | |
| SCHEMBL6489082 | 0.79 | CFD (0.46) | — | |
| SCHEMBL13574575 | 0.79 | PRMT5 (0.65) | PRMT5WDR77CYP2D6HIF1A | |
| SCHEMBL10400554 | 0.79 | FAAH (0.60) | CYP2D6CYP2C9HIF1AFAAHHRH3 | |
| SCHEMBL13574574 | 0.79 | PRMT5 (0.65) | PRMT5WDR77CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321534-A | Preparation method of high-purity medicinal roxatidine acetate hydrochloride | 哈药集团技术中心 | 2021-02-05 | — | — | CN | disclosed |