Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276252 | 0.87 | KDM4E (0.57) | HRH4FLT3IDO1DRD2DRD3 | |
| SCHEMBL13690245 | 0.85 | HPGD (0.52) | DRD2DRD3MMP1MMP9MMP12 | |
| SCHEMBL5635951 | 0.85 | MMP1 (0.51) | HRH4DRD2DRD3MMP1MMP9 | |
| SCHEMBL10508699 | 0.85 | MMP1 (0.51) | MMP1MMP9MMP12GAAGLA | |
| SCHEMBL10509285 | 0.84 | ALDH1A1 (0.50) | IDO1MMP1MMP9MMP12GAA | |
| SCHEMBL5355599 | 0.81 | GLA (0.68) | HRH4FLT3IDO1DRD2DRD3 | |
| SCHEMBL10507997 | 0.81 | HRH4 (0.52) | HRH4FLT3IDO1DRD2DRD3 | |
| SCHEMBL24019646 | 0.79 | IDO1 (0.62) | HRH4FLT3IDO1DRD2DRD3 | |
| SCHEMBL8869810 | 0.78 | RAB9A (0.57) | HRH4FLT3IDO1DRD2DRD3 | |
| SCHEMBL5289613 | 0.78 | DRD2 (0.59) | FLT3DRD2DRD3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835175-A | Indole derivatives pharmaceutical preparations based thereon, and β-receptor stimulation therewith | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |