Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378478 | 0.90 | SMN1; SMN2 (0.55) | LMNASIGMAR1ATMCARM1PRMT6 | |
| SCHEMBL11795494 | 0.80 | LMNA (0.62) | LMNASIGMAR1L3MBTL1ATMCARM1 | |
| SCHEMBL10846769 | 0.80 | TSHR (0.50) | LMNASIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL1088446 | 0.78 | SIGMAR1 (0.74) | LMNASIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL10695557 | 0.78 | SIGMAR1 (0.59) | LMNASIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL8399726 | 0.77 | L3MBTL1 (0.60) | LMNASIGMAR1L3MBTL1ATMMEN1 | |
| SCHEMBL5867104 | 0.77 | LMNA (0.56) | LMNASIGMAR1L3MBTL1ATMCARM1 | |
| SCHEMBL10843997 | 0.77 | LMNA (0.56) | LMNASIGMAR1L3MBTL1ATMCARM1 | |
| SCHEMBL10765990 | 0.77 | SIGMAR1 (0.62) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| Hydrochloric Acid SCHEMBL1087168 | 0.77 | SIGMAR1 (0.71) | LMNASIGMAR1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173933-B1 | 1,6-NAPHTHYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENT CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-11-29 | — | — | EP | claimed |
| US-4579859-A | HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-01 | — | — | US | disclosed |
| EP-0127150-A2 | 2,6-Disubstituted-1,4-dihydropyridine derivative, process for the preparation of the same and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-05 | — | — | EP | disclosed |