Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765990 | 0.95 | SIGMAR1 (0.62) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL11558833 | 0.89 | CARM1 (0.58) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL1088446 | 0.82 | SIGMAR1 (0.74) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL149999 | 0.82 | SIGMAR1 (0.59) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL29733117 | 0.81 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| Hydrochloric Acid SCHEMBL1087168 | 0.81 | SIGMAR1 (0.71) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL7225346 | 0.81 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL7284935 | 0.79 | SIGMAR1 (0.65) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL10508405 | 0.78 | LMNA (0.56) | SIGMAR1CARM1PRMT6PRMT8MAOB | |
| SCHEMBL7055109 | 0.78 | CARM1 (0.75) | SIGMAR1CARM1PRMT6PRMT8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |