Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508451 | 0.80 | L3MBTL1 (0.47) | PIN1PPARGPPARALTA4HSMN1; SMN2 | |
| SCHEMBL8219799 | 0.78 | LTA4H (0.42) | PIN1PPARGPPARALTA4HPPARD | |
| SCHEMBL8190164 | 0.75 | CYP4A11 (0.43) | PIN1PPARGPPARALTA4HSMN1; SMN2 | |
| SCHEMBL8225522 | 0.75 | PPIB (0.42) | PPARGLTA4HSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3184733 | 0.72 | ALDH1A1 (0.54) | PIN1LTA4HSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8186540 | 0.72 | PPARA (0.39) | PIN1PPARGPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL254781 | 0.71 | ALDH1A1 (0.53) | PIN1LTA4HSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8229645 | 0.71 | RAB9A (0.46) | SMN1; SMN2LMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL8191568 | 0.71 | MEN1 (0.49) | LMNAALDH1A1POLBL3MBTL1CYP1A2 | |
| SCHEMBL12268225 | 0.70 | TRPA1 (0.53) | PPARGPPARALMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298939-A1 | Metal-chelating 2,6-disubstituted pyridine compounds and their use | WALLAC OY (FI) | 1989-01-11 | — | — | EP | disclosed |