Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL104721 | 1.00 | CA1 (0.43) | CA1CA9BBOX1CA4FAHD1 | |
| Fumaric Acid SCHEMBL31550455 | 1.00 | CA1 (0.43) | CA1CA9BBOX1CA4FAHD1 | |
| Fumaric Acid SCHEMBL104718 | 1.00 | CA1 (0.43) | CA1CA9BBOX1CA4FAHD1 | |
| Fumaric Acid SCHEMBL106908 | 0.96 | — | — | |
| Fumaric Acid SCHEMBL107533 | 0.96 | — | — | |
| Fumaric Acid SCHEMBL21815723 | 0.95 | CA1 (0.45) | CA1CA9BBOX1CA4FAHD1 | |
| Fumaric Acid SCHEMBL6553031 | 0.95 | CA1 (0.45) | CA1CA9BBOX1CA4FAHD1 | |
| Fumaric Acid SCHEMBL6553020 | 0.95 | CA1 (0.45) | CA1CA9BBOX1CA4FAHD1 | |
| Fumaric Acid SCHEMBL23828619 | 0.91 | — | — | |
| Fumaric Acid SCHEMBL21815644 | 0.91 | CA1 (0.43) | CA1CA9BBOX1CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118460147-A | Preparation method and application of polyacrylic acid powder binder for lithium battery | 杭州叁元素赋能新材料有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-117343670-A | Adhesive for negative electrode of water-based lithium ion battery, and preparation method and application thereof | 杭州叁元素赋能新材料有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117039139-A | Polymer electrolyte membrane, preparation method thereof and secondary battery | 江苏清陶能源科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-114361456-B | Water-based functional ion-conducting binder for lithium battery, preparation method and application | 中国科学院化学研究所 | 2023-05-05 | — | — | CN | claimed |
| CN-113540697-B | Composite diaphragm and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-114361456-A | Water-based functional ion-conducting binder for lithium battery, preparation method and application | 中国科学院化学研究所 | 2022-04-15 | — | — | CN | claimed |
| CN-113540697-A | Composite diaphragm and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2021-10-22 | — | — | CN | claimed |
| EP-2621012-B1 | MANUFACTURING METHOD FOR ELECTROLYTE, ELECTROLYTE SOLUTION, GEL ELECTROLYTE, ELECTROLYTE MEMBRANE AND GEL ELECTROLYTE BATTERY, AND LITHIUM-ION SECONDARY BATTERY | SEKISUI CHEMICAL CO LTD (JP) | 2018-01-10 | — | — | EP | claimed |
| US-4041176-A | SOLVENTS, INSECTICIDES, AND AN ORGANIC LITHIUM COMPOUND MARKING AGENT | DESOWAG-BAYER HOLZSCHUTZ GMBH (DT) | 1977-08-09 | — | — | US | claimed |
| EP-4747927-A2 | SYNTHESIS OF NANOSTRUCTURED BATTERY MATERIALS | Coreshell Technologies, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| CN-122095492-A | Synthesis of nanostructured battery materials | — | 2026-05-26 | — | — | CN | disclosed |
| CN-115458808-B | Method for producing lithium fluorosulfonate, nonaqueous electrolyte solution, and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2026-05-15 | — | — | CN | disclosed |
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-04-30 | — | — | US | disclosed |
| US-20260044081-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-12 | — | — | US | disclosed |
| US-4910294-A | Two-stage process for production of polyarylene sulfides with lithium compound | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0355499-A2 | A process for preparing polyarylene sulfides | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0353717-A2 | Polyarylene sulfides, a process for preparing the same and a resin composition containing the same | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |
| EP-0296250-A1 | POLYARYLENE SULFIDE AND PROCESS FOR ITS PRODUCTION | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1988-12-28 | — | — | EP | disclosed |
| US-4118588-A | PROPIONIC ACID AND METHYL PROPIONATE REACTED WITH DIMETHOXYMETHANE, METAL PHOSPHATE AND/OR SILICATE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4041176-A | SOLVENTS, INSECTICIDES, AND AN ORGANIC LITHIUM COMPOUND MARKING AGENT | DESOWAG-BAYER HOLZSCHUTZ GMBH (DT) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260118767-A1 | REVERSE PATTERNING PROCESS | EFNA1, EPHA4, ETV6 | CA1 1449/4885CA9 505/4885BBOX1 4582/4885 |
| US-20260044081-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS | SMC1A, SPOUT1, LBR | CA1 964/4885CA9 1790/4885BBOX1 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.