SCHEMBL1050873

SCHEMBL1050873

Cc1ccc(-c2cccc(O)c2O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.48
ALDH1A1 P00352 6/20 0.46
HPGD P15428 5/20 0.46
HSD17B10 Q99714 5/20 0.46
ALOX15 P16050 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
RECQL P46063 3/20 0.46
LMNA P02545 3/20 0.46
ADAMTS4 O75173 1/20 0.46
EGFR P00533 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
FYN P06241 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
CA6 P23280 1/20 0.46
CDK2 P24941 1/20 0.46
MMP12 P39900 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29087185 0.94 TRPA1 (0.43) TRPA1ALDH1A1HPGDHSD17B10ALOX15
SCHEMBL1005237 0.89 MEN1 (0.46) TRPA1ALDH1A1HPGDHSD17B10ALOX15
Toluene SCHEMBL27814898 0.88 ALDH1A1 (0.56) TRPA1ALDH1A1HPGDHSD17B10ALOX15
SCHEMBL27536997 0.88 BCL2L1 (0.50) ALDH1A1HPGDHSD17B10BCL2L1MEN1
SCHEMBL29706607 0.85 MAOA (0.43) TRPA1ALDH1A1HPGDHSD17B10ALOX15
SCHEMBL30642011 0.83 TRPA1 (0.48) TRPA1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL28821934 0.83 TRPA1 (0.48) TRPA1ALDH1A1HPGDHSD17B10BCL2L1
SCHEMBL673890 0.83 ALDH1A1 (0.54) TRPA1ALDH1A1HPGDHSD17B10CA1
SCHEMBL22129996 0.83 HDAC4 (0.52) ALDH1A1HPGDHSD17B10TDP1LMNA
SCHEMBL894974 0.82 ALDH1A1 (0.65) ALDH1A1HPGDHSD17B10ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112020520-B Method for producing allyl monomer copolymer having polar group 国立大学法人东京大学 2023-03-10 CN disclosed
EP-2318477-B1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MAT USA INC (US) 2019-06-05 EP disclosed
US-8252704-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2012-08-28 US disclosed
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-10-27 US disclosed
US-7985350-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-07-26 US disclosed
EP-2318477-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FujiFilm Electronic Materials USA, Inc. (US) 2011-05-11 EP disclosed
US-20110091651-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-04-21 US disclosed
US-7871536-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-01-18 US disclosed
WO-2010005937-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2010-01-14 WO disclosed
US-20090291210-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2009-11-26 US disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives GPX4, GPX1, NFE2L2 TRPA1 2251/4885ALDH1A1 69/4885HPGD 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.