Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 5/20 | 0.51 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RIOX2 | Q8IUF8 | 3/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 5/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 7/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.44 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515854 | 0.96 | ASPH (0.50) | ASPHKDM8KDM4ERIOX2EGLN1 | |
| SCHEMBL10515374 | 0.83 | PKM (0.49) | PLA2G4B | |
| SCHEMBL1722473 | 0.76 | SMN1; SMN2 (0.57) | ASPHKDM8KDM4ERIOX2EGLN1 | |
| SCHEMBL29819483 | 0.75 | TSHR (0.44) | KDM4EMAPT | |
| SCHEMBL10764581 | 0.73 | HCAR2 (0.41) | ASPHKDM8KDM4EMAPT | |
| SCHEMBL2130083 | 0.73 | SMN1; SMN2 (0.57) | ASPHKDM8KDM4EKDM6BKDM4C | |
| SCHEMBL2743520 | 0.72 | HDAC1 (0.68) | MAPTRXFP1PLA2G4BHDAC1 | |
| SCHEMBL2402134 | 0.72 | HDAC1 (0.68) | MAPTRXFP1PLA2G4BHDAC1 | |
| SCHEMBL11563158 | 0.72 | HCAR3 (0.67) | ASPHKDM8KDM4ERIOX2EGLN1 | |
| SCHEMBL19857480 | 0.72 | GABRP (0.46) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330470-A2 | 1,4-Dihydropyridine derivatives useful against tumour cells | AJINOMOTO CO., INC. (JP) | 1989-08-30 | — | — | EP | claimed |