Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518366 | 0.88 | MAPT (0.53) | LSSROCK1ROCK2LTA4HADORA2A | |
| SCHEMBL10520078 | 0.86 | LSS (0.39) | LSSROCK1ATP4AATP4BCYP3A4 | |
| SCHEMBL10520818 | 0.85 | HPGD (0.48) | HPGDTRPM8SMN1; SMN2HRH2HRH4 | |
| SCHEMBL10521863 | 0.85 | LSS (0.50) | LSSROCK1ROCK2LTA4HADORA2A | |
| SCHEMBL10623949 | 0.83 | HRH2 (0.47) | ROCK1PRKACASMN1; SMN2HRH2 | |
| SCHEMBL10519858 | 0.76 | TSHR (0.43) | LSSROCK1ROCK2LTA4HCYP3A4 | |
| SCHEMBL10519095 | 0.75 | ALDH1A1 (0.44) | LTA4HHPGDSMN1; SMN2HRH2HRH4 | |
| SCHEMBL10520529 | 0.75 | ALDH1A1 (0.46) | HPGDSMN1; SMN2NOS1HRH2HRH4 | |
| SCHEMBL10521322 | 0.75 | MAPT (0.55) | LSSROCK1ROCK2HPGDTRPM8 | |
| SCHEMBL10519036 | 0.73 | ALDH1A1 (0.53) | LSSROCK1CYP3A4PRKACAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |