Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522292 | 0.85 | PTPRB (0.51) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL11419906 | 0.84 | HIF1A (0.48) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL3679227 | 0.81 | THRA (0.67) | ALDH1A1SMN1; SMN2TSHRTHRATHRB | |
| SCHEMBL2564390 | 0.81 | ALDH1A1 (0.82) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL29954798 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRTHRATHRBKEAP1 | |
| Hydrochloric Acid SCHEMBL10411183 | 0.76 | ALDH1A1 (0.57) | ALDH1A1THRATHRBKEAP1PTPRB | |
| SCHEMBL18427948 | 0.76 | IDO1 (0.57) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL18427979 | 0.76 | IDO1 (0.57) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL19714971 | 0.76 | IDO1 (0.57) | ALDH1A1SMN1; SMN2HIF1ALMNAMAPT | |
| SCHEMBL70271 | 0.76 | KEAP1 (0.74) | SMN1; SMN2MAPTKEAP1PTPRBCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810422-A | CARCINOSTATS OF LOW TOXICITY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0259185-A1 | Bile acid derivatives, their salts and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-03-09 | — | — | EP | disclosed |