Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | PTEN | P60484 | 1/20 | 0.51 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519820 | 0.85 | ALDH1A1 (0.56) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL3679227 | 0.81 | THRA (0.67) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL27649319 | 0.79 | KEAP1 (0.61) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL29954798 | 0.78 | ALDH1A1 (0.58) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| Hydrochloric Acid SCHEMBL10411183 | 0.76 | ALDH1A1 (0.57) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL70271 | 0.76 | KEAP1 (0.74) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL3242805 | 0.75 | KEAP1 (0.61) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL11331980 | 0.74 | THRB (0.53) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| Hydrochloric Acid SCHEMBL10982620 | 0.74 | KEAP1 (0.71) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL11427939 | 0.73 | CSF3R (0.44) | PTPRBCDC25ACDC25BPTENPTPMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810422-A | CARCINOSTATS OF LOW TOXICITY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0259185-A1 | Bile acid derivatives, their salts and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-03-09 | — | — | EP | disclosed |