Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PTEN | P60484 | 1/20 | 0.50 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341529 | 0.86 | THRA (0.52) | THRATHRBALDH1A1CYP3A4FFAR1 | |
| SCHEMBL11341527 | 0.86 | THRA (0.52) | THRATHRBALDH1A1CYP3A4FFAR1 | |
| SCHEMBL11331980 | 0.85 | THRB (0.53) | THRATHRBKEAP1ALDH1A1PTPRB | |
| SCHEMBL29954798 | 0.83 | ALDH1A1 (0.58) | THRATHRBKEAP1ALDH1A1PTPRB | |
| SCHEMBL11334796 | 0.83 | THRA (0.53) | THRATHRBALDH1A1CYP3A4CNR2 | |
| Hydrochloric Acid SCHEMBL10411183 | 0.82 | ALDH1A1 (0.57) | THRATHRBKEAP1ALDH1A1PTPRB | |
| SCHEMBL11340512 | 0.82 | THRB (0.52) | THRATHRBALDH1A1CYP3A4PPARG | |
| SCHEMBL10519820 | 0.81 | ALDH1A1 (0.56) | THRATHRBKEAP1ALDH1A1PTPRB | |
| SCHEMBL5593618 | 0.81 | CYP1A2 (0.49) | THRATHRBALDH1A1CYP3A4FFAR1 | |
| SCHEMBL10522292 | 0.81 | PTPRB (0.51) | THRATHRBKEAP1ALDH1A1PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812038-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-10-12 | — | — | US | disclosed |
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | BIEDIGER RONALD J | 2006-12-07 | — | — | US | disclosed |
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | disclosed |
| US-4243606-A | AZO DYE COUPLER INTERMEDIATES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | VCAM1, ICAM1, ITGA1 | THRA 195/4885THRB 395/4885KEAP1 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.