Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 2/20 | 0.34 |
| ▸ | KDM4B | O94953 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520147 | 0.91 | LSS (0.41) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10517590 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10519858 | 0.86 | TSHR (0.43) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10519036 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10521863 | 0.79 | LSS (0.50) | ALDH1A1MAPTKMT2ALSSTSHR | |
| SCHEMBL10518550 | 0.78 | TSHR (0.56) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10518291 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10520446 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10520078 | 0.76 | LSS (0.39) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10871169 | 0.75 | KDM4B (0.34) | ALDH1A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |