Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4B | O94953 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519036 | 0.88 | ALDH1A1 (0.53) | LSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10521093 | 0.86 | LSS (0.47) | LSSATP4AATP4BCYP3A4RAB9A | |
| SCHEMBL10520147 | 0.85 | LSS (0.41) | LSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10869929 | 0.79 | ATP4A (0.35) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10517590 | 0.79 | ALDH1A1 (0.52) | LSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10520529 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10520818 | 0.77 | HPGD (0.48) | KMT2AALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL10521092 | 0.76 | ALDH1A1 (0.37) | LSSMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10519095 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10518366 | 0.73 | MAPT (0.53) | LSSMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |