Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 2/20 | 0.32 |
| ▸ | KDM5C | P41229 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519036 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10521092 | 0.89 | ALDH1A1 (0.37) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10520147 | 0.80 | LSS (0.41) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10518366 | 0.79 | MAPT (0.53) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10520078 | 0.79 | LSS (0.39) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10519514 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10519858 | 0.75 | TSHR (0.43) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10868925 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10520584 | 0.72 | ALDH1A1 (0.72) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10619839 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |