Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521837 | 1.00 | ALDH1A1 (0.33) | ALDH1A1ELANEMMP9GAARAB9A | |
| SCHEMBL10519252 | 0.91 | MMP9 (0.32) | MMP9MMP2MMP3 | |
| SCHEMBL10519245 | 0.91 | MMP9 (0.32) | MMP9MMP2MMP3 | |
| SCHEMBL10522966 | 0.86 | REN (0.35) | MMP9MMP2 | |
| SCHEMBL10522964 | 0.86 | REN (0.35) | MMP9MMP2 | |
| SCHEMBL10521853 | 0.83 | SMN1; SMN2 (0.36) | ALDH1A1MMP2MMP3ATM | |
| SCHEMBL9800539 | 0.76 | ALDH1A1 (0.34) | ALDH1A1GAARAB9AATMMAPT | |
| SCHEMBL10519903 | 0.73 | SIGMAR1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL10519904 | 0.73 | SIGMAR1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL8486197 | 0.73 | HRH4 (0.45) | MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863904-A | Dipeptides as renin inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0181110-A2 | Histidine derivatives as renin inhibitors | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-05-14 | — | — | EP | disclosed |