Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TYMS | P04818 | 5/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521999 | 0.83 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL10518577 | 0.80 | TSHR (0.39) | ALDH1A1MAPTMEN1KMT2ADHFR | |
| SCHEMBL10649686 | 0.79 | NR1H2 (0.38) | ALDH1A1MAPTMEN1KMT2ADHFR | |
| SCHEMBL10519474 | 0.75 | DHFR (0.52) | ALDH1A1MAPTMEN1KMT2ATYMS | |
| SCHEMBL10522322 | 0.72 | MAPT (0.66) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| Nitrobenzene SCHEMBL10522235 | 0.72 | ALDH1A1 (0.43) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL10522672 | 0.71 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2ATYMS | |
| SCHEMBL24494887 | 0.69 | THRB (0.40) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL10521296 | 0.69 | MAPT (0.51) | ALDH1A1MAPTMEN1KMT2ATYMS | |
| SCHEMBL18154731 | 0.69 | MAPT (0.56) | ALDH1A1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797146-A | INSECTICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0226885-A1 | Pyrimidylmercapto-acylanilides | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |