Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | TDP2 | O95551 | 2/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10525620 | 0.85 | MEN1 (0.52) | PKMTSHRMEN1KMT2ACDC25B | |
| SCHEMBL10524699 | 0.76 | NSD2 (0.50) | PKMTSHRMAOALMNAMAPT | |
| SCHEMBL10524736 | 0.76 | S100A4 (0.59) | MAOAPTPRCS100A4CES1MAOB | |
| SCHEMBL5137019 | 0.76 | PKM (0.58) | PKMTSHRMEN1KMT2ACDC25B | |
| SCHEMBL10522898 | 0.74 | MALT1 (0.44) | MAOAPTPRCIDO1MAOBALDH1A1 | |
| SCHEMBL10522287 | 0.74 | ESR2 (0.63) | MAOAMAPTRAB9AIDO1MAOB | |
| SCHEMBL6966321 | 0.73 | PKM (1.00) | PKMTSHRMEN1KMT2ACDC25B | |
| SCHEMBL10522834 | 0.72 | LMNA (0.50) | MEN1KMT2AMAOAPTPRCLMNA | |
| SCHEMBL1664813 | 0.72 | PTPRC (0.65) | PKMTSHRMEN1KMT2ACDC25B | |
| Anthraquinone SCHEMBL1901249 | 0.71 | MEN1 (1.00) | TSHRMEN1KMT2ACDC25BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840965-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1989-06-20 | — | — | US | disclosed |