Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517400 | 0.93 | HTR2A (0.42) | HTR2ASLC6A4KCNH2CETPTHRB | |
| SCHEMBL10516472 | 0.84 | HTR2A (0.41) | HTR2ASLC6A4KCNH2CETPTHRB | |
| SCHEMBL9794574 | 0.84 | MTNR1A (0.35) | HTR2ATHRBARTHRA | |
| SCHEMBL10523936 | 0.81 | FFAR1 (0.50) | CETPTHRBFFAR1THRA | |
| SCHEMBL10517017 | 0.81 | AR (0.36) | HTR2ASLC6A4KCNH2THRBAR | |
| SCHEMBL10516372 | 0.80 | AR (0.37) | HTR2ASLC6A4KCNH2THRBAR | |
| SCHEMBL9711446 | 0.78 | TRPV4 (0.35) | HTR2ASLC6A4KCNH2THRBAR | |
| SCHEMBL10516760 | 0.77 | HTR2A (0.39) | HTR2ASLC6A4KCNH2CETPTHRB | |
| SCHEMBL11041547 | 0.76 | KIF11 (0.41) | AR | |
| SCHEMBL3104195 | 0.74 | TLR7 (0.39) | HTR2ASLC6A4KCNH2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313908-A2 | Halogen-substituted phenoxyphenylpropionic acid derivatives | BAYER AG (DE) | 1989-05-03 | — | — | EP | disclosed |