Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714062 | 0.80 | AR (0.36) | PLA2G7THRBHTR2ASLC6A4KCNH2 | |
| SCHEMBL9711431 | 0.79 | RAB9A (0.42) | THRBTHRA | |
| SCHEMBL9750971 | 0.78 | PTPN7 (0.48) | THRBMRGPRX4PPARGTHRASMN1; SMN2 | |
| SCHEMBL10523904 | 0.78 | HTR2A (0.39) | THRBHTR2ASLC6A4KCNH2AR | |
| SCHEMBL9640700 | 0.77 | THRB (0.37) | PLA2G7THRBMRGPRX4KDM4ETHRA | |
| SCHEMBL11041547 | 0.77 | KIF11 (0.41) | MRGPRX4ARSCN9AKDM4E | |
| SCHEMBL10441387 | 0.77 | TLR7 (0.35) | PLA2G7THRBTDP1CYP3A4PPARG | |
| SCHEMBL9634929 | 0.77 | RAB9A (0.41) | THRBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9488250 | 0.77 | CYP3A4 (0.33) | THRBMRGPRX4ALDH1A1MAPTTDP1 | |
| SCHEMBL9794574 | 0.76 | MTNR1A (0.35) | THRBHTR2AARHPGDTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315008-B1 | DERIVATIVES OF (6-(HETERO)ARYLOXY-NAPHTHALIN-2-YL-OXY)ALCANOIC ACID | BAYER AG (DE) | 1992-09-09 | — | — | EP | disclosed |
| US-5079384-A | Weed killers, destroy broad leaf plants, postemergence | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |
| EP-0315008-A2 | Derivatives of (6-(hetero)aryloxy-naphthalin-2-yl-oxy)alcanoic acid | BAYER AG (DE) | 1989-05-10 | — | — | EP | disclosed |