Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847870 | 0.73 | ALDH1A1 (0.43) | KDM4EAPAF1NPC1TDP2S1PR4 | |
| SCHEMBL9847843 | 0.71 | LMNA (0.38) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL29002632 | 0.70 | CHRM2 (0.48) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL9847891 | 0.70 | KDM4E (0.34) | KDM4ENPC1RAB9APAX8P2RX7 | |
| SCHEMBL9847871 | 0.70 | KDM4E (0.35) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL10530512 | 0.69 | GPR174 (0.38) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL9847821 | 0.68 | KDM4E (0.36) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL9847872 | 0.67 | GPR174 (0.37) | LMNAKDM4ENPC1MAPTMAPK1 | |
| SCHEMBL27533046 | 0.66 | LMNA (0.87) | LMNAKDM4EAPAF1NPC1TDP2 | |
| SCHEMBL30638926 | 0.66 | FSCN1 (0.54) | NPC1MAPTRAB9AP2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1011587-B | PROCESS FOR THE PREPARATION OF QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE | KYORIN SEIYAKU KK (JP) | 1991-02-13 | — | — | CN | disclosed |
| EP-0183129-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| CN-86102363-A | The preparation method of Carbostyril carboxylic acid derivatives and application thereof | — | 1987-01-21 | — | — | CN | disclosed |
| EP-0195841-A1 | Quinolinecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-10-01 | — | — | EP | disclosed |
| EP-0195316-A1 | Quinolonecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-09-24 | — | — | EP | disclosed |
| CN-85109026-A | The preparation method and its usage of Carbostyril carboxylic acid derivatives | — | 1986-07-30 | — | — | CN | disclosed |
| EP-0183129-A1 | Quinolonecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-06-04 | — | — | EP | disclosed |