Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216477 | 0.84 | MAPT (0.34) | GPR174SLC6A4NOS3NOS1NOS2 | |
| SCHEMBL2216243 | 0.81 | SLC6A4 (0.44) | SLC6A4NOS3NOS1NOS2LMNA | |
| SCHEMBL9847843 | 0.79 | LMNA (0.38) | SLC6A4LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL10530512 | 0.79 | GPR174 (0.38) | GPR174NOS3NOS1NOS2LMNA | |
| SCHEMBL9301104 | 0.76 | ALDH1A1 (0.43) | SLC6A4ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL9847870 | 0.70 | ALDH1A1 (0.43) | SLC6A4ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL31208163 | 0.69 | ALDH1A1 (0.68) | SLC6A4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL12933618 | 0.69 | SLC6A4 (0.39) | SLC6A4LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL29686582 | 0.69 | SLC6A4 (0.43) | SLC6A4ALDH1A1KDM4EVCAM1HTT | |
| SCHEMBL26118511 | 0.69 | SLC6A4 (0.43) | SLC6A4ALDH1A1KDM4EVCAM1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |