Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524519 | 0.93 | LTA4H (0.42) | LTA4HTSHRALDH1A1ADRB2CYP3A4 | |
| SCHEMBL11678077 | 0.91 | LTA4H (0.44) | LTA4HCYP2C9CYP2C19ADRB2CYP3A4 | |
| SCHEMBL4352158 | 0.84 | TSHR (0.34) | TSHRALDH1A1GAAMAPT | |
| SCHEMBL2572166 | 0.82 | L3MBTL1 (0.40) | TSHRL3MBTL1ALDH1A1MAPTALOX12 | |
| SCHEMBL11671814 | 0.82 | FAAH (0.41) | LTA4HTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11868100 | 0.81 | ALDH1A1 (0.39) | CYP1A2TSHRL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11864912 | 0.81 | ALDH1A1 (0.42) | CYP1A2TSHRALDH1A1GAAMAPT | |
| SCHEMBL11683656 | 0.77 | MAOB (0.35) | CYP1A2TSHRALDH1A1CYP3A4MAPT | |
| SCHEMBL11671527 | 0.75 | ALDH1A1 (0.41) | CYP2C9CYP2C19CYP1A2TSHRL3MBTL1 | |
| SCHEMBL159324 | 0.73 | LTA4H (0.46) | LTA4HCYP2C9CYP2C19CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845235-A | Pyrroline derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-07-04 | — | — | US | disclosed |