Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10528929 | 0.83 | ALDH1A1 (0.47) | HTTTDP1L3MBTL1 | |
| SCHEMBL7867611 | 0.81 | IDO1 (0.50) | RAB9AAKR1C3IDO1NPC1 | |
| SCHEMBL6645015 | 0.79 | RAB9A (0.61) | HTR2ARAB9AAKR1C3HTTIDO1 | |
| SCHEMBL37664 | 0.79 | HTR2A (0.62) | HTR2ARAB9AAKR1C3HTTIDO1 | |
| SCHEMBL5827968 | 0.78 | HTR2A (0.80) | HTR2ARAB9AAKR1C3HTTIDO1 | |
| SCHEMBL10490876 | 0.77 | HTR2A (0.67) | HTR2ARAB9AAKR1C3HTTIDO1 | |
| SCHEMBL1714950 | 0.77 | HTR2A (0.70) | HTR2ARAB9AHTTNPC1TDP1 | |
| SCHEMBL8201751 | 0.77 | KMT2A (0.51) | TDP1 | |
| SCHEMBL10490758 | 0.76 | HTR2A (0.58) | HTR2ARAB9AAKR1C3HTTIDO1 | |
| SCHEMBL4725847 | 0.76 | HTR2A (0.59) | HTR2ARAB9AAKR1C3HTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308559-A2 | Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |