Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797 | 0.87 | ALDH1A1 (0.42) | KMT2AMEN1LMNATDP1MCHR1 | |
| SCHEMBL2036605 | 0.74 | HTT (0.40) | KMT2AMEN1LMNATDP1 | |
| SCHEMBL12076557 | 0.74 | LMNA (0.47) | KMT2AGAALMNATDP1ALDH1A1 | |
| SCHEMBL6045 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1GAALMNAALDH1A1 | |
| SCHEMBL6047 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1GAALMNAALDH1A1 | |
| SCHEMBL12764522 | 0.73 | TXNRD1 (0.48) | — | |
| SCHEMBL10279 | 0.72 | MAPT (0.44) | KMT2AMEN1LMNATDP1MCHR1 | |
| SCHEMBL2034821 | 0.72 | ELANE (0.43) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10193193 | 0.68 | TDP1 (0.50) | KMT2AMEN1GAATDP1ALDH1A1 | |
| SCHEMBL2027839 | 0.67 | JAK2 (0.42) | KMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |