Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531 | 0.87 | KMT2A (0.41) | ALDH1A1LMNATDP1KMT2AMEN1 | |
| SCHEMBL12076557 | 0.78 | LMNA (0.47) | ALDH1A1LMNAHTTTDP1KMT2A | |
| SCHEMBL2036605 | 0.76 | HTT (0.40) | LMNAHTTTDP1KMT2AMEN1 | |
| SCHEMBL10279 | 0.74 | MAPT (0.44) | ALDH1A1LMNAHTTTDP1POLB | |
| SCHEMBL2034821 | 0.73 | ELANE (0.43) | ALDH1A1HTTKMT2AMEN1MAPT | |
| SCHEMBL6775 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTTDP1POLB | |
| SCHEMBL6773 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTTDP1POLB | |
| SCHEMBL2027839 | 0.71 | JAK2 (0.42) | LMNAHTTTDP1KMT2AMAPT | |
| SCHEMBL12764522 | 0.69 | TXNRD1 (0.48) | — | |
| SCHEMBL29772903 | 0.67 | USP30 (0.53) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |