Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333243 | 0.83 | SMN1; SMN2 (0.62) | FFAR1KEAP1HPGDALOX15TDP1 | |
| SCHEMBL29499090 | 0.83 | SMN1; SMN2 (0.62) | FFAR1KEAP1HPGDALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL28672925 | 0.81 | SMN1; SMN2 (0.60) | FFAR1KEAP1HPGDALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL4174816 | 0.81 | SMN1; SMN2 (0.60) | FFAR1KEAP1HPGDALOX15TDP1 | |
| SCHEMBL18906068 | 0.80 | L3MBTL1 (0.57) | KEAP1HPGDL3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL6643327 | 0.79 | LMNA (0.69) | HPGDALOX15TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2774503 | 0.79 | FFAR1 (0.83) | FFAR1KEAP1TBXAS1FFAR4SMN1; SMN2 | |
| SCHEMBL29373231 | 0.78 | L3MBTL1 (0.68) | ALOX15TDP1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL64435 | 0.78 | L3MBTL1 (0.68) | ALOX15TDP1L3MBTL1SMN1; SMN2CYP1A2 | |
| Ethylene Glycol SCHEMBL11535314 | 0.78 | SMN1; SMN2 (0.57) | FFAR1KEAP1HPGDALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882433-A | 3'-pyridinylalkylinden- and 3'-pyridinylalkylindol-2-carboxylic acids and analogs | THE UPJOHN COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
| US-4767865-A | 3'-pyridinylalkylinden- and 3'-pyridinylalkylindol-2-carboxylic acids and analogs | THE UPJOHN COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0247089-A1 | 3'-PYRIDINYLALKYLINDEN- AND 3'-PYRIDINYLALKYLINDOL-2-CARBOXYLIC ACIDS AND ANALOGS | THE UPJOHN COMPANY (US) | 1987-12-02 | — | — | EP | disclosed |
| WO-1987002664-A1 | 3'-PYRIDINYLALKYLINDEN- AND 3'-PYRIDINYLALKYLINDOL-2-CARBOXYLIC ACIDS AND ANALOGS | THE UPJOHN COMPANY (US) | 1987-05-07 | — | — | WO | disclosed |