Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544853 | 0.84 | ALDH1A1 (0.45) | ALDH1A1CNR2NPC1RAB9AKDM4E | |
| SCHEMBL10548265 | 0.81 | THRA (0.41) | CNR2THRATHRBHPGDMEN1 | |
| SCHEMBL10547136 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2AMAOB | |
| SCHEMBL10546055 | 0.76 | MLYCD (0.51) | ALDH1A1LMNAKMT2A | |
| SCHEMBL11133367 | 0.75 | HDAC6 (0.55) | ALDH1A1CNR2THRATHRB | |
| SCHEMBL8472203 | 0.74 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL13381405 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2THRATHRB | |
| SCHEMBL27600929 | 0.73 | CNR2 (0.52) | ALDH1A1CNR2THRATHRB | |
| SCHEMBL10544541 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL10422627 | 0.71 | EPHX2 (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |