Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546639 | 0.86 | KMT2A (0.43) | KMT2AALDH1A1GAATSHRKDM4E | |
| SCHEMBL10548133 | 0.74 | PSEN1 (0.53) | KMT2AALDH1A1KDM4EMEN1TAS2R14 | |
| SCHEMBL10548265 | 0.69 | THRA (0.41) | KMT2AMEN1MAOB | |
| SCHEMBL6415769 | 0.65 | RIPK1 (0.62) | KMT2AALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL54682 | 0.64 | KMT2A (0.46) | KMT2AALDH1A1GAATSHRKDM4E | |
| SCHEMBL20621832 | 0.64 | TAAR1 (0.50) | KMT2AALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL10544541 | 0.63 | SMN1; SMN2 (0.43) | KMT2AALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL25062411 | 0.62 | HDAC1 (0.45) | ALDH1A1TSHRKDM4ESMN1; SMN2HDAC8 | |
| SCHEMBL10547136 | 0.62 | ALDH1A1 (0.48) | KMT2AALDH1A1MEN1LMNAMAOB | |
| SCHEMBL13235820 | 0.62 | ALDH1A1 (0.44) | KMT2AALDH1A1KDM4EMEN1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |