Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026185 | 0.86 | NPC1 (0.57) | NPC1EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL10548838 | 0.84 | CNR1 (0.66) | NPC1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL11030224 | 0.82 | KMT2A (0.59) | NPC1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL11027327 | 0.82 | RAB9A (0.64) | NPC1EPHX2MEN1KMT2AROCK2 | |
| SCHEMBL11051112 | 0.81 | RAB9A (0.60) | NPC1EPHX2MEN1KMT2AROCK2 | |
| SCHEMBL11266342 | 0.81 | EPHX1 (0.74) | NPC1EPHX1MEN1KMT2AROCK2 | |
| SCHEMBL5638898 | 0.79 | NAMPT (0.60) | MEN1KMT2AROCK2ROCK1NAMPT | |
| SCHEMBL10545814 | 0.78 | TAS1R3 (0.61) | MEN1KMT2AROCK2ROCK1TAS1R3 | |
| SCHEMBL11029084 | 0.78 | NPC1 (0.53) | NPC1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL6382679 | 0.78 | EPHX1 (0.68) | NPC1EPHX1EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438110-A | 1-(MONO-SUBSTITUTED PHENYL)-3-BENZOYL UREA AND A PHOSPHOROUS CONTAINING COMPOUND | UNION CARBIDE CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |