Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546758 | 0.87 | RIPK1 (0.51) | RIPK1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL10549243 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10547820 | 0.81 | PDK1 (0.47) | ALDH1A1LMNAKMT2AMEN1MAOB | |
| SCHEMBL662742 | 0.79 | RIPK1 (0.64) | RIPK1ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6182681 | 0.77 | KMT2A (0.69) | RIPK1ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL2634610 | 0.76 | RIPK1 (0.64) | RIPK1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL10543666 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10544372 | 0.75 | RIPK1 (0.51) | RIPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL29565583 | 0.74 | RIPK1 (0.65) | RIPK1KMT2AMEN1PYCR1PTGES | |
| SCHEMBL28958770 | 0.73 | HSP90AA1 (0.58) | RIPK1ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |