Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958718 | 0.85 | SCD5 (0.53) | HSP90AA1HSD17B2HSD17B1ALDH1A1HPGD | |
| SCHEMBL28958704 | 0.77 | NSD2 (0.51) | ALDH1A1HPGDLMNAKMT2AMEN1 | |
| SCHEMBL18773897 | 0.77 | KMT2A (0.69) | HSP90AA1HSD17B2HSD17B1ALDH1A1HPGD | |
| SCHEMBL13114705 | 0.75 | HSP90AA1 (0.56) | HSP90AA1HSD17B2HSD17B1ALDH1A1KMT2A | |
| SCHEMBL18773963 | 0.74 | MEN1 (0.60) | HSP90AA1HSD17B2HSD17B1HPGDKMT2A | |
| SCHEMBL20677844 | 0.74 | HSP90AA1 (1.00) | HSP90AA1PDK1 | |
| SCHEMBL10548973 | 0.73 | RIPK1 (0.53) | HSD17B2HSD17B1ALDH1A1HPGDLMNA | |
| SCHEMBL19182758 | 0.73 | HSP90AA1 (0.68) | HSP90AA1HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL15645684 | 0.72 | HSD17B2 (0.56) | HSP90AA1HSD17B2HSD17B1ALDH1A1HPGD | |
| SCHEMBL14524623 | 0.72 | HSP90AA1 (0.53) | HSP90AA1HSD17B2HSD17B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |